Knowledge Check • The Blood Project

What are causes of microcytosis?

a

HbCC

b

HbEE

c

Beta-thalassemia

d

Alpha-thalassemia

e

Chronic kidney disease

Click for Answer

1. Target cells
2. Irregularly contracted cells

True of false: HbCC is associated with reduced mean corpuscular hemoglobin concentration (MCHC).

a

True

b

False

HbCC is associated with elevated MCHC.

Sort the cause of anemia according to whether the red blood cells are typically small (microcytic) or large (macrocytic):

Hypothyroidism

Iron deficiency

Hb E disorders

Lead poisoning

Thalassemia

Hb C disorders

Microangiopathic hemolytic anemia

Hydroxyurea

Liver disease

Vitamin B12 deficiency

Anemia of inflammation

Alcohol

Microcytic

Macrocytic