Knowledge Check

Which of the following statements about reticulocytes is/are true:

a
They are reported as a % of total red cells or as an absolute number
b
They decrease the mean cell volume (MCV)
They tend to increase the MCV because they are larger than mature red cells.
c
By definition, they cannot actually be seen on a routine (Wright-Giemsa-stained) blood film
By definition, reticulocytes are defined by the presence of clumped granular material called reticulum on a special reticulocyte stain. They may also be detected by flow cytometry after staining with an RNA-binding fluorochrome. Reticulocytes appear as polychromatophilic cells seen on a Wright- or Wright-Giemsa-stained blood film.
d
An absolute reticulocyte count > 120 x 10^9/L is considered an appropriate bone marrow response to anemia

True or false: there is a factor V available for treating patients with factor V deficiency.

a
True
b
False