Knowledge Check

Sorting exercise

Drag and drop the cards with causes of thrombocytopenia on the top to the bucket that coincides with the typical clinical setting on the bottom.

Medication effect

Infection

Cirrhosis

Extracorporeal circuit

Antiphospholipid syndrome (APS)

Gestational thrombocytopenia

Dilutional thrombocytopenia

HELLP

Familial thrombocytopenia

Alcohol toxicity

Thrombotic thrombocytopena purpura (TTP)

Immune thrombocytopenia (ITP)

ITP with bleed

Outpatient

Urgent care

Inpatient

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Matching exercise

Drag and drop the conditions on the left to the corresponding smear findings on the right.

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Cirrhosis

TTP

PTP

Platelet clumping

Schistocytes

Target cells, acanthocytes

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PTP, pseudothrombocytopenia; TTP, thrombotic thrombocytopenia purpura

Matching exercise

Drag and drop the platelet count thresholds on the left to the corresponding platelet counts on the right.

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Threshold for increased risk of bleeing

Threshold for ITP diagnosis

Threshold for treating ITP

Platelet count < 30K

Platelet count < 10K

Platelet count < 100K

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Which is more common:

True of false: immune thrombocytopenia is a diagnosis of exclusion.

Sorting exercise

Drag and drop the cards on the top into their corresponding buckets on the bottom.

TPO receptor agonists

Corticosteroids

IVIG

Rituximab

First-line therapy

Second-line therapy

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True of false: all patients with new onset immune thrombocytopenia (ITP) should receive rituximab.