Knowledge Check

Sorting exercise

Drag and drop the cards with causes of thrombocytopenia on the top to the bucket that coincides with the typical clinical setting on the bottom.

Dilutional thrombocytopenia

Antiphospholipid syndrome (APS)

Infection

Familial thrombocytopenia

Extracorporeal circuit

Medication effect

ITP with bleed

Immune thrombocytopenia (ITP)

Cirrhosis

HELLP

Gestational thrombocytopenia

Thrombotic thrombocytopena purpura (TTP)

Alcohol toxicity

Outpatient

Urgent care

Inpatient

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Matching exercise

Drag and drop the conditions on the left to the corresponding smear findings on the right.

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PTP

Cirrhosis

TTP

Platelet clumping

Schistocytes

Target cells, acanthocytes

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PTP, pseudothrombocytopenia; TTP, thrombotic thrombocytopenia purpura

Matching exercise

Drag and drop the platelet count thresholds on the left to the corresponding platelet counts on the right.

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Threshold for treating ITP

Threshold for increased risk of bleeing

Threshold for ITP diagnosis

Platelet count < 30K

Platelet count < 100K

Platelet count < 10K

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Which is more common:

True of false: immune thrombocytopenia is a diagnosis of exclusion.

Sorting exercise

Drag and drop the cards on the top into their corresponding buckets on the bottom.

Rituximab

TPO receptor agonists

Corticosteroids

IVIG

First-line therapy

Second-line therapy

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True of false: all patients with new onset immune thrombocytopenia (ITP) should receive rituximab.