Knowledge Check
Sort lab test (top) according to whether it is typically altered in TTP or not (bottom):
Low ADAMTS13
Increased reticulocytes
Low haptoglobin
Elevated PT and/or aPTT
Spur cells in smear
Elevated ADAMTS13
Stool positive for Shiga toxin
Elevated AST
Elevated LDH
Positive DAT
Schistocytes on smear
Elevated direct bilirubin
Elevated ALT
Altered in TTP
Not altered in TTP
Abbreviations: TTP, thrombotic thrombocytopenic purpura; LDH, lactate dehydrogenase; DAT, direct antiglobulin test; PT, prothrombin time; aPTT, activated partial thromboplastin time.
