Knowledge Check • The Blood Project

What are causes of microcytosis?

a

HbCC

b

HbEE

c

Beta-thalassemia

d

Alpha-thalassemia

e

Chronic kidney disease

Click for Answer

1. Target cells
2. Irregularly contracted cells

True of false: HbCC is associated with reduced mean corpuscular hemoglobin concentration (MCHC).

a

True

b

False

HbCC is associated with elevated MCHC.

Sort the cause of anemia according to whether the red blood cells are typically small (microcytic) or large (macrocytic):

Alcohol

Thalassemia

Iron deficiency

Hypothyroidism

Hb E disorders

Microangiopathic hemolytic anemia

Hydroxyurea

Hb C disorders

Anemia of inflammation

Lead poisoning

Vitamin B12 deficiency

Liver disease

Microcytic

Macrocytic