• Patients were randomized 1:1 to treatment arms:
    • Dexamethasone 40 mg PO daily for 4 days
    • Prednisone 1 mg/kg/day for 4 weeks followed by taper
  • In the high-dose dexamethasone arm, an additional 4-day course of dexamethasone was given if platelet count remained < 30,000 or there were bleeding symptoms by day 10
  • In the prednisone arm, prednisone was tapered after 4 weeks in responders. The taper schedule was determined by treating clinicians but was supposed to be over 4-6 weeks.
  • Requirement for additional ITP-modifying intervention during follow-up was considered treatment failure
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