Anemia – Classification

Kinetic (reticulocyte count) and morphological (mean cell volume) classification of anemia. The morphological classification may be extended to include mean corpuscular hemoglobin concentration (MCHC), which separates microcytic anemias into normochromic (thalassemia) and hypochromic (iron deficiency anemia). Anemia of inflammation, while typically normocytic, may be mildly microcytic and hypochromic. DAT, direct antiglobulin test; HA, hemolytic anemia; TMA, thrombotic microangiopathy; MAHA, macroangiopathic hemolytic anemia; SCD, sickle cell disease; HS, hereditary spherocytosis; HE, heredity elliptocytosis; PHN, paroxysmal nocturnal hemoglobinuria; Def, deficiency; PKD, pyruvate kinase deficiency. primary BM, primary bone marrow condition.