Before going any further, let’s take stock of what we know. You are being asked to see a patient with ischemic stroke and an elevated aPTT.
aPTT, activated partial thromboplastin time
What are causes of acquired elevation in the activated partial thromboplastin time (aPTT) with normal prothrombin time?
You are doing well! Let’s keep going. What are additional causes of acquired elevation of aPTT with normal prothrombin time?
An elevated aPTT is often indicative of a bleeding diathesis. Why did this patient develop a clot, and not a hemorrhage?
Besides lupus anticoagulant, what are other causes of an elevated aPTT in the setting of a thrombus?Click for Answer
True or false: Lupus anticoagulant, heparin induced thrombocytopenia (HIT), disseminated intravascular coagulation (DIC), and liver disease – all causes of an elevated aPTT + thrombosis, are also associated with thrombocytopenia.